Linical Trial Drugs Regulations and Manufacture

This is an industry based thesis ,its about the pharmaceutical companies out look on the trials whats involved from there prospective,who is involved , sponors etc the different phases , what the requirements or directives are from the regulatory bodies , fda , emea, ich, mhra etc also how to apply to the regulators what forms are needed .The differnces between regulations , example: how does the GCP directive compare to the ICH GCP .Manufacturing of clinical trial drugs , what the requirements are from start to release , one example the requirements for packaging labelling. Other subjects -what is a clinical drug trial/history of clinical drug trials/importance of clinical drug trials.