Oes Crocus sativus L. (Saffron) assist in the treatment of Depression?

Im a Herbal Medicine student in my final days of school. i missed the deadline for my dissertation due to health problems.
The main problem was deep depression and im still not over it. Ive tried different herbs and the one that seems to be working is saffron (Crocus sativus L.).

The Dissertation Proposal should be approximately 500 words excluding references. So I marked 3 pages (750 words ) but not sure how it is going to be enough. please let me know.

Im also not sure about the title of the dissertation. could you please let me know if it is interesting or should i change. please advise.
After this order of The Dissertation Proposal
Ill need more of your help I might order orderthe Dissertation”


S
hould follow the school Dissertation guidelines listed below:
Final year dissertation Overview 2009/2010


What it is:

Your dissertation should be an in depth study on a subject (in your specialist field, i.e. Herbal Medicine or Acupuncture) chosen by you
The study consists of a broad literature review (approx. 15-40 articles, not just a few)
Each student will be allocated a personal tutor for help and guidance
It carries 12.5% weighting towards the final numerical mark awarded for the course.

You are NOT investigating the effects of a herb or an acupuncture treatment!

You are investigating what evidence there is for a certain effect


Aim of the dissertation:

To give you the opportunity to do a guided review of a topic you are specifically interested
To make you aware of the value of research which can help you in your practice to help with diagnosis, prognosis and treatment options
To make you aware of shortfalls in research and possibilities to overcome them.
To encourage your own research
To give a flavour of what is required to publish your own article


Choice of Dissertation subject:

The subject must correlate with Herbal Medicine or acupuncture, respectively.
It should be mainly guided by your own interest.
It needs to be sufficiently specific to allow a concise and rounded write up.
It will need to be approved by the dissertation coordinator.


Some sample titles (from previous years)

Herbal Medicine
Is Echinacea a safe herb for use in the treatment of autoimmune conditions?
Does Vitex agnus castus assist in the treatment of premenstrual syndrome?
Does Rhodiola rosea possess vitality, longevity and anti-aging qualities?
Acupuncture
Does Acupuncture increase the success rate of in vitro fertilisation?
How effective is acupuncture in alleviating the symptoms of morning sickness in pregnancy?
Is there evidence that acupuncture has a significant therapeutic effect on migraine headache?
Acceptable study texts are:

RCTs
Case control studies
Cohort studies
In vitro studies
Animal studies

Studies must be clinically relevant


The overall process:

Read the dissertation guidelines (plus the article by Klass et al.) carefully!
Identify an area of your interest (within your chosen specialist area).
Review the literature
Write a proposal of approx. 500 words and submit to the head of research.
Wait for approval, then go ahead with your research.

For the following parts use your personal tutor for help, feedback and suggestions

Submit outline to your personal tutor
Submit sections to your personal tutor
Final dissertation will be marked by the personal tutor and a second marker.

Organisation of the dissertation ( hour glass structure)

Introduction
Lead reader from general subject to a particular research question
2. Body
Stays within a tight thematic scope
Discussion
Tries to draw general conclusions and relates to other people s work

Finer details

Title
Should identify the main issue of the paper
Begin with the subject of the paper
Is accurate, unambiguous, specific and complete
Does not contain abbreviations and
Attracts the reader

Abstract
Is usually one paragraph and includes:
Motivation: Why do we care about the problem and the results?
Problem statement: What problem is the paper trying to solve and what is the scope of the work?
Approach: What was done to solve the problem?
Results: What is the answer to the problem?
Conclusions: What implications does the answer imply?

Introduction
Establish a territory
Establish a niche
Occupy the niche

The introduction should guide the reader to the current understanding (text book knowledge)

Body
Methods: Sources, search keywords, inclusion/exclusion criteria
Results possible with sections of various aspects (in vivo, in vitro, main effects, side effects, combinations, etc.// Western approach, TCM, Five element // case studies, RCTs, etc.)
Analysis:
A descriptive analysis details the different studies and summarises the key points.
One good accessible way of presenting this is in a table. The table should provide a summary of the evidence of each study and a judgement on the methodological rigour.
You will have to decide what comparisons to make and then summarise the comparisons (possibly in a table).
The next step is to systematically investigate the differences and make a judgement about the effect of the intervention across the studies. The crucial questions that must be addressed are listed here:
Questions for considerations
What comparisons should be made?
What results should be used in each comparison?
How similar are the results within each comparison?
How can you best summarise the effects for each comparison?
How reliable are those summaries?

Discussion and Conclusions
Presentation of background information as well as recapitulation of the research aims of the present study
Brief summary of results (more discussion than recapitulation)
Comparing and contrasting various studies and their results
Comparison of results with previously known facts (e.g. textbook)
Conclusions or hypothesis drawn from the results, with evidence
Proposed follow-up research questions

References
Follow the referencing guideline: (Harvard system Name and year system)




Proposal

Chose a topic or a couple of topics
Review the literature (at least 20 abstracts and 5-10 full length articles) using PubMed and Google (Scholar) and specialist journals.
Ask an appropriate specific question, which should be the problem you want to study and will give you the title of your dissertation
Write a proposal which contains:
Your Name
Name of Research Module leader (Pia Huber)
Introduction (text book knowledge, Motivation)
Aim (Hypothesis); Problem statement
Methods (searches, exclusion  inclusion criteria); Approach
Preliminary Results
References

Marking Criteria (for proposal as well as for final dissertation):
Information Gathering  15%
Organisation and Structure  10%
Use of Evidence  15%
Analysis and Arguments  40%
Presentation  10%
Overall impression of the Proposal  10%
Total  100%

Time Plan for the Dissertation  Keep your tutor informed
Proposal  September 2009 (first study day at the CNM)
Approval and Tutor allocation by Christmas 2009
Grotty first draft (for Tutor)  31 Jan 2010
Presentable second draft (for Tutor)  10 April 2010
Good third draft  30 June